Scientific papers

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ODT: Study of the influence of the lubricant ratio on the tabletting properties of PEARLITOL® Flash
Orodispersible | Case study
PEARLITOL® Flash has been developed as a self-disintegrating mannitol compound for the formulation of ODTs by direct compression. Thanks to its special composition, a very low level of lubricant is necessary.
ODT: Study of the dilution potential of PEARLITOL® Flash formulated with acetaminophen
Orodispersible | Case study
See how PEARLITOL® Flash allows the production of robust orodispersible tablets even at high dilution.
ODT: Study of the disintegrating properties of PEARLITOL® Flash
Orodispersible | Case study
PEARLITOL® Flash is a compound of mannitol and starch, specially designed to disintegrate rapidly, providing a smooth texture without the addition of a superdisintegrant. In the present study, PEARLITOL® Flash's disintegration properties and mechanism were evaluated.
Benzocaine degradation in oral disintegrating tablet platforms
Orodispersible | Scientific paper
The aim of the study is to determine if commercially available oral disintegrating tablet (ODT) platforms induce active pharmaceutical ingredient (API) degradation.
Preparation and characterization of Zaleplon solid dispersions by cyclodextrin complexation
Solid dispersions | Scientific paper
The present study is focusing on Zaleplon complexation with cyclodextrins (CDs) by different solid dispersion methods and compares their efficacy by dissolution.
Zaleplon solubility enhancement by native and modified betacyclodextrin
Solubility enhancement | Scientific paper
The objective of this project is to evaluate the ability of native and modified betacyclodextrins to enhance Zaleplon solubility.
Griseofulvin Taste Masked by Hot Melt Extrusion for Pediatric and Geriatric Reconstitutable Suspension
Taste masking | Scientific paper
The main objective here was to investigate the potential of Kleptose Linecaps DE17 in masking the bitter taste of antifungal drug by Hot Melt Extrusion and to formulate a reconstitutable suspension for pediatric / geriatric patients.

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