Formulation assistance

Our technical sales unit is composed of pharmacists and technologists, highly qualified experts in their fields, who will be pleased to help you.

Our research and technology team can offer you the support of some of the best equipped formulation laboratories in the world.

We invite you to discover them and other world-class services here and see how they can assist you in your product developments.

Understanding powder properties is essential to efficient tablet manufacture. Parameters such as bulk density, compressibility, hygroscopicity, particle size, flowability and dust formation need to be controlled.

Once the powders have been carefully chosen they must be prepared for either compression or to fill sachets or hard capsules. The quality of the product depends on correctly mixing, coloring, flavoring, etc. Other steps such as wet or dry granulation are critical to ensuring homogeneity. In our application laboratories we study all these operations, including compaction, a technology which is fast becoming the industry reference.

Compression converts the powder into tablets. Three factors--compression forces, punch design and type of press--are essential for end-product quality and ease of production. Our laboratories are equipped with a range of presses dedicated to aiding optimum formulation and evaluating behavior in industrial conditions.

Once the tablets have been manufactured, quality control testing is indispensable. The usual parameters such as hardness, thickness, weight, density, friability, and disintegration and dissolution times are monitored. Other methods have also been established to obtain a better understanding of tablet features. One of these is observing appearance using electron microscopy or Instron measurements.

Many confectionery products can be used as vectors for actives. These include gums, hard candies (stamped or deposited) and chewing gums. Roquette has over 30 years of experience in sugar-free confectionery and this expertise is readily applicable to pharmaceutical formulations.

For several decades Roquette has been the leading global producer of polyols for oral care. We have played a major role in assisting customers in developing diverse formulations, be they white, translucent, clear or opaque, paste or liquid, or whether they contain actives, baking soda or microbeads. Roquette also possesses expertise in novel oral care measures, including oral strips and tongue-scratching candies to counter halitosis.

Formulating a syrup is not necessarily a simple task. Many parameters have to be controlled to suit the active ingredients, including pH, color stability, precipitation, suspension and separation, crystallization and cap-locking.

In this area, too, we have the expertise and equipment to help you develop any formulation.

The Roquette team has been helping to design pharmaceutical formulations for over 30 years. Working closely with customers under confidentiality agreements, we develop as many as 50 formulations a year. We offer expertise for every step of manufacturing, across a wide range of applications.

Please contact us to find out how we can help you.