Case studies

Roquette has long been viewed as a “solution provider”, helping to resolve difficult formulation problems through close relations with major pharmaceutical and cosmetic development teams.
pH adjustment of Lycoat solution for acid sensitive substrates

This study evaluates how to apply a Lycoat® based coating solution on acid sensitive substrates.

(Registration required)

LYCOAT - Coating at ambiant temperature

This study evaluates how to achieve a perfect coating at ambient temperature protecting heat sensitive ingredients or dosage forms.

(Registration required)

Film coating: Effect of inert fillers quantity on coating quality

Pigments are used in coating formulations for very different purposes. Having a strong effect on film mechanical property, it’s essential to know what maximum quantity of fillers a coating formulation can withstand, so as to combine good film forming ability with excellent tablet property.
(Registration required)

ODT: Study of the disintegrating properties of PEARLITOL® Flash

PEARLITOL® Flash is a compound of mannitol and starch, specially designed to disintegrate rapidly, providing a smooth texture without the addition of a superdisintegrant.
In the present study, PEARLITOL® Flash's disintegration properties and mechanism were evaluated.
(Registration required)

 

ODT: Study of the dilution potential of PEARLITOL® Flash formulated with acetaminophen

In the present study, the dilution potential was evaluated using acetaminophen.
Conclusion:  PEARLITOL® Flash allows the production of robust orodispersible tablets even at high dilution.
(Registration required)

 

ODT: Study of the influence of the lubricant ratio on the tabletting properties of PEARLITOL® Flash

PEARLITOL® Flash has been developed as a self-disintegrating mannitol compound for the formulation of ODTs by direct compression. Thanks to its special composition, a very low level of lubricant is necessary.
(Registration required)

 

Film coating: Incidence of the quantity of polymer

Coating tablets is a delicate balance between a homogeneous color and unimpaired disintegration properties. This can be achieved with a proper amount of coating deposit at the surface of the tablet.
(Registration required)