Case studies

Roquette has long been viewed as a “solution provider”, helping to resolve difficult formulation problems through close relations with major pharmaceutical and cosmetic development teams.
Film coating: Effect of inert fillers quantity on coating quality

Pigments are used in coating formulations for very different purposes. Having a strong effect on film mechanical property, it’s essential to know what maximum quantity of fillers a coating formulation can withstand, so as to combine good film forming ability with excellent tablet property.
(Registration required)

ODT: Study of the disintegrating properties of PEARLITOL® Flash

PEARLITOL® Flash is a compound of mannitol and starch, specially designed to disintegrate rapidly, providing a smooth texture without the addition of a superdisintegrant.
In the present study, PEARLITOL® Flash's disintegration properties and mechanism were evaluated.
(Registration required)

 

ODT: Study of the dilution potential of PEARLITOL® Flash formulated with acetaminophen

In the present study, the dilution potential was evaluated using acetaminophen.
Conclusion:  PEARLITOL® Flash allows the production of robust orodispersible tablets even at high dilution.
(Registration required)

 

ODT: Study of the influence of the lubricant ratio on the tabletting properties of PEARLITOL® Flash

PEARLITOL® Flash has been developed as a self-disintegrating mannitol compound for the formulation of ODTs by direct compression. Thanks to its special composition, a very low level of lubricant is necessary.
(Registration required)

 

Film coating: Incidence of the quantity of polymer

Coating tablets is a delicate balance between a homogeneous color and unimpaired disintegration properties. This can be achieved with a proper amount of coating deposit at the surface of the tablet.
(Registration required)